Alcon to Acquire LumiThera, Expanding Retinal Portfolio with Breakthrough AMD Therapy

Acquisition adds FDA-cleared Valeda® Light Delivery System to Alcon’s pipeline, targeting early and intermediate dry age-related macular degeneration through photobiomodulation technology

The acquisition of LumiThera by Alcon represents a strategic partnership designed to address one of the most pressing unmet needs in ophthalmology: early and intermediate-stage dry age-related macular degeneration (AMD). While current treatment options largely target the disease in its late stages, LumiThera’s photobiomodulation (PBM) device introduces a proactive, non-invasive therapy aimed at improving vision and preserving retinal health before irreversible damage occurs. By bringing LumiThera’s technology under its umbrella, Alcon aims to leverage its global commercial reach and clinical expertise to deliver this novel treatment to a broader patient population, shifting the standard of care toward earlier intervention.

The PBM device has already shown strong clinical validation through multiple LIGHTSITE trials, where it demonstrated sustained visual improvement, reduced dependence on additional therapies, and a high safety profile. Its use of low-level, non-laser light to stimulate mitochondrial function in retinal cells offers a unique therapeutic pathway that differs from pharmacological or surgical options. With FDA de novo market authorization and CE Mark already secured, the technology is poised for wider adoption across key markets. Alcon’s ability to integrate this device into routine ophthalmology practice—particularly in outpatient clinical settings—can significantly improve accessibility and treatment adherence for aging populations at risk of AMD-related vision loss.

Ultimately, the partnership is expected to deliver long-term impact in both clinical and market terms. It enhances Alcon’s innovation pipeline, adds a first-in-class solution to the dry AMD space, and supports LumiThera’s vision of offering early, effective care to millions worldwide. By combining LumiThera’s cutting-edge technology with Alcon’s distribution, regulatory, and educational infrastructure, the collaboration is set to elevate global standards in retinal disease management—marking a significant step toward preserving vision and quality of life in an increasingly aging population.


MedTech Spectrum's Summary 
 
Strategic Advancement in Retinal Care: Alcon’s acquisition of LumiThera brings the first non-invasive photobiomodulation (PBM) therapy for early and intermediate dry AMD into its portfolio—addressing a major clinical gap with a proven, vision-improving treatment.
 
Strong Clinical Backing & Market Readiness: Backed by successful LIGHTSITE trials and FDA/CE approvals, LumiThera’s PBM device has demonstrated sustained visual acuity gains with no serious adverse effects, enabling Alcon to accelerate global adoption through its commercial infrastructure.
 
Expanded Global Impact: This acquisition enables earlier intervention for millions at risk of vision loss, reinforcing Alcon’s leadership in eye care and setting a new standard for treating dry AMD before irreversible damage occurs.