ILC Dover, an Ingersoll Rand business and world leader in the innovative design and production for biopharmaceutical, pharmaceutical, and medical device markets, announced the capabilities of its EZJetFlo technology, an advanced in-line powder induction and mixing system designed to help biopharmaceutical manufacturers simplify operations, improve consistency, and accelerate production.

Efficient powder dissolution remains a critical challenge in bioprocessing, where incomplete wetting, powder agglomeration, and long mixing times can impact batch quality, process efficiency, and scalability. EZJetFlo addresses these challenges through a Venturi-based design that rapidly entrains powders into a high-velocity liquid stream, enabling immediate wetting, dispersion, and dissolution in a fully closed, single-use process.

Recent testing documented in the whitepaper, Enhancing Biopharmaceutical Production Through Advanced Mixing: Boosting Performance with EZJetFlo Technology, demonstrated significant improvements in powder induction and mixing performance at a 900-liter scale.

The system operates in closed-loop recirculation mode, where accelerated liquid flow creates a vacuum of approximately –900 mbar, drawing powders directly into the process stream. This approach eliminates many of the limitations associated with traditional vessel-based mixing methods while providing consistent flow dynamics and streamlined operation.

"Biopharmaceutical manufacturers are under constant pressure to improve productivity while maintaining product quality and process control," said Paulo Bento, Director, Process Equipment & Field Applications. "EZJetFlo Technology delivers a scalable, efficient solution that helps customers reduce processing times, improve mixing consistency, and simplify operations in media and buffer preparation applications."